Safe Handling of Cytotoxic Drugs


Closed System Drug Transfer Device 

Closed System Drug Transfer Device – Occupational Exposure to Anti-Cancer Drug

Even after getting potential suggestions from health professional and researchers, the health-care workers are still struggling with major health problems due to the exposure to hazardous drugs at workplace.  The healthcare organizations and hospitals must concentrate more on conducting an awareness programs on biological safety and total protect against the exposure to toxic drugs. Currently health organizations are taking few measurement steps to prevent the issue, but it is not sufficient enogh to eradicate the major risks related to hazardous drugs. 

Preventing workplace infectivity is the best approach to reduce cytotoxic drug exposure in healthcare workers. The researchers conducted a study to compare the personnel exposure and surface contamination generated by cyclophosphamide before and after using CSTD.

• Personnel exposure was pertained by collecting 24hour urine samples from four pharmacists. The personnel test conducted on 4 pharmacists, 24hour urine test showed positive results. The tests resulted high contamination levels in both groups personnel exposure and surface contamination.  But, after using the Equashield innovative device, the levels were dropped to its minimal level for 2 pharmacists

• Surface contamination was evaluated with wiping test.  4 of 6 wipe samples are showed high level of chyclophosphmide level on the surface.  But, after using closed surface drug transfer device only one wipe among 6 showed the detectable level.  i

• In combination with Closed System Drug Transfer Device and maintaining hygiene can further reduces the risks occurs due to exposure to toxic drugs. CSTD reduces surface contamination and exposure to cyclophosphamide drugs to undetectable levels. After implementing CSTD at workplace many healthcare professionals are feeling safe and secure to handle toxic drugs.

Many drugs that are used for cancer treatment contains toxic compounds and they are considered to be most dangerous to healthcare workers. From past 20 years various studies are conducted on environmental contamination caused by hazardous drugs in healthcare centers and hospital pharmacies.  Toxic drugs were unintentionally immersed, as resolute by the existence of parent compounds or their metabolites obtained in the urine of pharmaceutical workers and causing severe health conditions, sometime it can be fatal too.

Due to the probable health risks of toxic drugs, many health organizations are trying to educate healthcare workers as the usage of these drugs has been increased so as the environmental contamination. Therefore, the NIOSH (National Institute for Occupations Safety and Health) published a vigilant for antineoplastic and other toxic drugs used in hospitals and clinics. These guidelines can help and educate the staff.  also they highlighted the problems caused by toxic drugs.

Closed System Transfer Device was designed by Equashield helps prevent contamination at working place during transferring the drug between the vial and syringe.  The implementation of the device has been providing successful results as it helps stop contamination levels and protecting healthcare workers from exposure to toxic drugs.